by Office of Governor Patrick

Question posed by 22akgirl: Questions on cystic fibrosis!!?
what organism(s) does cystic fibrosis affect and how?
how frequently does the mutation occur
what are some high-risk demographics?
what is the average life expectancy?
what is the death rate
what are some treatments?

thanks:)
i meant demographics not demographies:)

No 1 answer:

Answer by Matt A
http://www.mamashealth.com/cfibrosis.asp

http://www.wrongdiagnosis.com/c/cf/stats.htm

http://www.disabled-world.com/health/respiratory/cystic-fibrosis/life-expectancy.php

http://www.cff.org/AboutCF/

Try these websites to answer your question.

If you know better then please let us know below.

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Question by AJ S: Questions about Cystic Fibrosis?
I was just wondering if a toddler could be diagnosed with cystic fibrosis even if they haven’t exhibited respiratory symptoms. anyone have any information for a scared mommy waiting for a phone call?

The No 1 answer:

Answer by Hattie
Yes, sorry to say it bluntly though! Try not to worry, I’m sure they will be fine, and even if the news is that they have CF, there are plenty of helping hands out there. Your not on your own, so don’t worry!

Hope your both okay!

Provide your own answer to this question below!

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by Tanya Dawn

A question from wanajoust: Chemistry Questions – What is a catalyst? Why are enzymes considered catalysts?…?
Give a good explanation to the following:

1. What is a catalyst? Why are enzymes considered catalysts?

2. Diagram (and label) an enzyme-substrate complex.

3. Explain, in layman’s terms, the mechanism of action (how does it work?)

4. Approximately how many enzymes are at work in the human body? Why are enzymes vital to the life of organisms?

5. What is the general term for conditions that arise as a result of a lack of enzymes in the body? (Think about it)

6. What caused the condition that affected the blue people of Kentucky?

7. What causes Tay Sachs disease?

8. What causes cystic fibrosis?

9. Jello packages warn that using fresh fruit such a pineapple or papaya will prevent jello from solidifying?However, cooking pineapple (or other fresh fruit) then adding it to the Jello will not affect its ability to gel. Explain this.

10. Some individuals have adverse reactions to consuming products like nutrasweet? What is the relationship between this and the enzyme phenylalanase?

Top answer:

Answer by Nathan
1. A catalyst is something that speeds up a reaction (eg heat)

Whether you agree or disagree, why not leave your own thoughts below.

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by k-ideas

Question posed by BobbyBill: Please Help: Genetics questions?
1. Is it possible for incomplete dominant and codominant alleles to be homozygous and heterozygous?

2. Would a karyoptype reveal the presence of cystic fibrosis, sickle-cell disease and hemophilia?

3. Also, can somebody explain to me about multiple allele traits and multiple gene traits? How are they the same, and how are they different?

My chosen answer:

Answer by Asst Prof
1. Yes, since heterozygous means “having different seeds,” a genotype showing two different alleles, LIke RW (for pink flowers) or AB (for blood type AB) is technically heterozygous. Similarly, if both alleles are the same, the gene is homozygous (having the same seed),

2. No. Those are defects in alleles, which cannot be seen on a karyotype. A karyotype will show only *chromosome* defects (like extra or broken chromosomes).

3. Most genes have ony 2 alleles, like red or white flowers, or tall or short. Genes with more than 2 alleles are cases of multiple allelic genes; human blood types are an example, with 3 alleles, A, B, and i. Multiple gene traits are traits that are controlled by more than one gene, all exerting their effects. Human skin tone is thought to be the result of 12 genes exerting their effects; thsi is why we have a wide range of skin colors, not just black or whte.

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Technorati Tags: GENETICS, help, PLease, questions

by windy_sydney

Question by ♥: Can someone answer these anatomy questions?
1.(A) DESCRIBE HOW YOUR NASAL PASSAGES REACT WHEN YOU FIRST GO OUTSIDE ON A VERY COLD DAY.
(B) WHY IS THIS GOOD/BAD?
2. (A) DESCRIBE HOW YOUR NASAL PASSAGES REACT WHEN YOU
ENTER AN AREA THAT IS FILLED WITH CIGARETTE SMOKE.
(B) WHY OR WHY NOT DO YOU THINK IT IS OKAY TO SMOKE?
3. FIND AND EXPLAIN THE LATEST RESEARCH ON SPIRAL CT SCANS AND EARLY DETECTION OF LUNG CANCER. CITE THE URL YOU USE.
4. WHAT CAUSES CYSTIC FIBROSIS AND HOW DOES IT AFFECT THE RESPIRATORY SYSTEM?
5. WHAT CAUSES TUBERCULOSIS AND HOW DOES IT AFFECT THE RESPIRATORY SYSTEM?
6. WHAT CAUSES CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND HOW DOES IT AFFECT THE RESPIRATORY SYSTEM?
7. (A) WHAT CAUSES ASTHMA AND HOW DOES IT AFFECT THE RESPIRATORY SYSTEM?
(B) DO YOU THINK ASTHMATICS SMOKE?
8. LIST 5 REASONS SMOKING IS BAD.
9. WHAT CAUSES PNEUMONIA AND HOW DOES IT AFFECT THE RESPIRATORY SYSTEM?
10. WHAT CAUSES PLEURISY AND HOW DOES IT AFFECT THE RESPIRATORY SYSTEM?

No 1 answer:

Answer by Lemon
Do your own homework

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by Tanya Dawn

Question by Mack ….: Help with genetics questions?
Can someone please help in answering the following…

1. In a certain population, 40 of every 1000 births resulted in an individual that suffers from cystic fibrosis. Assuming equilibrium, what is the allele frequency of the recessive allele that causes cystic fibrosis?

2. Cystic fibrosis is the most common autosomal recessive disorder in children of European descent. A couple has already had 3 girls with cystic fibrosis, and were hoping to have a normal child for their fourth. What are the chances that the fourth child will be a normal male?

3. In a certain breed of dog, black color (B) is dominant over red (b), and solid color (S) is dominant over spotted (s). If the genes are unlinked and the offspring of BBss and bbss individuals are mated with each other, what fraction of their offspring will be black and spotted?

4. Cleft chin is a X-linked dominant trait. If a man with a cleft chin marries a woman with a round chin, what percent of their female progeny will show the cleft chin trait?

No 1 answer:

Answer by Cris W
OK, won’t do the homework for you but here are some hints.

1. Use the Hardy-Weinberg equation, p2+ 2pq + q2 = 1. You know that Q2=40/1000. Proceed from there :>)

2. Remember that previous births don’t affect this one. You know the ratio of males to females, and (presuming neither parent has CF) you know the likelihood of two parents, each carrying a recessive gene, giving birth to a child with two copies of that gene. Multiply together and you have your answer.

3. Note that all individuals carry the recessive spotting gene. Note that one parent carries only the dominant black gene. If you can’t figure out what this means, use a Punnet square.

4. How many X chromosomes does a man have? What does he “donate” to an offspring that determines sex? What, therefore, must any of his female offspring have?

Whether you agree or disagree, why not leave your own thoughts below.

Technorati Tags: GENETICS, help, questions

Question posed by Pree Kay: Questions regarding Cystic Fibrosis. See details.?
-What specific part of the cell/structure allows the mucus secretions to be thick and viscous rather than fluid (i.e., is it a membrane channel, organelle or something else)? Please be specific and describe the step-by-step mechanism whereby this altered structure/part of the cell causes the secretions to contain less water.
-Why does Alvin have salt crystals forming on his skin? Explain the mechanism for this.
-What is the accepted treatment for children with cystic fibrosis? Make sure to list at least three and explain why they work (i.e., what is the purpose of each individual treatment).
-List and explain the mechanism of at least two experimental treatments that are currently being tried to help patients with cystic fibrosis.
-Briefly describe how gene therapy may help cure a genetically inherited disease like cystic fibrosis.

link to website with more info (like who alvin is) http://www.sciencecases.org/cf/cf.asp

If you can’t answer all the questions (only some) that’s better than nothing.

Selected answer:

Answer by Amber..=]
it may be here, and if not you could add anyway. spread the word. find a cure,

http://profile.myspace.com/index.cfm?fuseaction=user.viewprofile&friendid=406168417

What do you think? Leave you answer below!

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by fakelvis

Question by Sadsadsad Sadsadsadas: Can anyone please answer these questions on cystic fibrosis?
cystic fibrosis
1. What is the cause of this disease? Gene therapy is a possibility for future treatments.
2.What are the pros and cons of gene therapy.
3. What are the pros and cons of genetic testing for this disease (cystic fibrosis) ?
4.Who should be tested?
5. Who should be able to access the results of the genetic test results of a genetic test (parents, doctors, patients, insurance companies, etc.)

Best answer:

Answer by gangadharan nair
Cystic Fibrosis: This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

Whether you agree or disagree, why not leave your own thoughts below.

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by Tanya Dawn

Question posed by hello: can you help me with cystic fibrosis activity questions?
1. Cut out the DNA sequence patterns and tape them together so that they read:
CTT TTA TAG TAG ATA CCA CAA AGG
2. You just built a part of the gene that can cause cystic fibrosis
3. Now build a strand of mRNA that matches your DNA pattern as a complementary
strand.
4. Now the cell uses tRNA to bring the correct amino acids into position. You will model
this by using the mRNA code to determine which amino acids tRNA should bring.
The genetic code chart shows which bases code for which amino acids.
5. Please write the sequence of amino acids on your paper.
6. Now you will change the original DNA. A mutation!
Change the nucleotide in the 15th position (from the left) to cytosine.
7. Now follow the steps 3-5 to determine what affect this mutation would have on the
protein made by the gene.
8. Please write the sequence of amino acids after the mutation on your paper.
9. Now you will change your DNA again! A mutation (from the original DNA strand)!
Remove the nucleotides in the 13th, 14th, and 15th position. Shift the rest of the pieces to
close the gap.
10. Now follow the steps 3-5 to determine what affect this mutation would have on the
protein made by the gene.
11. Please write the sequence of amino acids after the mutation on your paper.

Questions: Please answer all 5 questions on a separate piece of paper
1. Did changing the sequence of DNA always result in a different amino acid sequence?
Are all mutations bad? Explain your answer.
2. If the adenine in the 15th position of the sequence is changed to a guanine, the person
does not have CF. However, if the thymine in the 14th position is changed to cytosine
the person does have CF. What are some reasons this might occur?
3. Where might the mutations in the original DNA come from? How does this happen
in real life?
4. What do you think would happen if a single nucleotide were added somewhere in the
sequence? Explain your answer.
5. Explain which kinds of mutations would result in a more serious form of CF. In your
explanation write about why some mutations are worse than others. Be sure to show you
understand how mutations affect the final protein!

No 1 answer:

Answer by cfkid
please call the cf hotline i can help you with this issue the number is 612-282-1211 hope to hear from you soon im also a patient and know alot about cystic fibrosis and im willing to help you in anyway that i can im also a nursing asst and a home health care aide as well

How about adding your own answer to the comments below!

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by mcbill

Question posed by jacket2230: Cystic Fibrosis questions?
After a scare with my nephew, my pediatrician and I discussed doing DNA testing through Ambry genetics. We did go through with it and my 5 year olds test have came back and he has G576A on exon 12 and R668C on exon 13. What does this mean? Does he have CF? Is there a such thing as mild CF? or could he just be a carrier? Thanks in advance.
not that the discussion with the dr has ended there. I have a wonderful relationship with my pediatrician, but as we all know they do not specialize in everything so I am waiting on an appointment with a pulmonary Dr. Also, if you have ever played the waiting game with your children and a possible illness you would search any and all avenues. So that is why I’m reaching out to other people who have possibly gone through the same thing. i would appreciate a little more compassion, but you must be one of those nurses who just need to get out while you can…..
Also still waiting on results for my 3 year old son
Thanks for your input hels. Your the kind of people I need to talk to who actually know about real life.
Thank you Barry M. I do have an email sent to Steve Keils the Director over Ambry genetics and I am waiting on his response. He does have his number listed so I’m tempted to pick up the phone today and just give him a call. Thanks

The top answer:

Answer by heogog
You really need to call the doc back and ask those questions to him. If you weren’t given that information at your appointment, then the doctor owes you a detailed breakdown on what all that means.
YA isn’t the place to be asking those kinds of really important specific questions.

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Technorati Tags: cystic, fibrosis, questions