Population Genetics?
A question from Cindy Choi: Population Genetics?
Cystic fibrosis (CF) is a non-sex-linked, recessive trait. In certain populations, the number of people born who, with repect to cystic fibrosis, are phenotypically normal is about 9900 in 10,000.
a. what are the frequencies of the normal and CF alleles?
b. what are the genotypic frequencies of homozygous normal, heterozygous, and homozygous affected individuals?
c. assuming radom mating, what is the probability that two phenotypically normal heterzygous carriers will chose each other as mates?
Chosen answer:
Answer by petrochirus
you have to figure out how the frequency of the CF allele. you can do this by figuring out the frequency of people that express the recessive phenotype. Then you set that equal to q^2. I am assuming you know Hardy Weinberg genetics so that should get you the rest of the way.
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