Genetics Help Please?

Question posed by Ashley P: genetics help please?
if one in every 22 people in the U.S is a carrier for Cystic fibrosis(autosomal recessive disease) what proportion of the U.S population would be expect to have c.f.?

The No 1 answer:

Answer by gotaprofquestion
1 in 22 x 1 in 22 = 1 in 484

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Genetics Help Please?

cystic fibrosis genetics
by mcbill

Question posed by Ashley P: genetics help please?
if one in every 22 people in the U.S is a carrier for Cystic fibrosis(autosomal recessive disease) what proportion of the U.S population would be expect to have c.f.?

My chosen answer:

Answer by gotaprofquestion
1 in 22 x 1 in 22 = 1 in 484

What do you think? Leave you answer below!

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Please Help: Genetics Questions?

Question posed by BobbyBill: Please Help: Genetics questions?
1. Is it possible for incomplete dominant and codominant alleles to be homozygous and heterozygous?

2. Would a karyoptype reveal the presence of cystic fibrosis, sickle-cell disease and hemophilia?

3. Also, can somebody explain to me about multiple allele traits and multiple gene traits? How are they the same, and how are they different?

My chosen answer:

Answer by Asst Prof
1. Yes, since heterozygous means “having different seeds,” a genotype showing two different alleles, LIke RW (for pink flowers) or AB (for blood type AB) is technically heterozygous. Similarly, if both alleles are the same, the gene is homozygous (having the same seed),

2. No. Those are defects in alleles, which cannot be seen on a karyotype. A karyotype will show only *chromosome* defects (like extra or broken chromosomes).

3. Most genes have ony 2 alleles, like red or white flowers, or tall or short. Genes with more than 2 alleles are cases of multiple allelic genes; human blood types are an example, with 3 alleles, A, B, and i. Multiple gene traits are traits that are controlled by more than one gene, all exerting their effects. Human skin tone is thought to be the result of 12 genes exerting their effects; thsi is why we have a wide range of skin colors, not just black or whte.

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Genetics Question Please Help!!?

A question from sherry: Genetics Question please help!!?
1 in 1700 US Caucasian newborns have cystic fibrosis. “C” for normal is dominant over “c” for cystic fibrosis. What is the frequency percentage of the cystic fibrosis allele?
a. 97.6%b. 0.059%c. 2.4%d. 0.01%

Top answer:

Answer by Asst Prof
(c).

If the frequency of cystic fibrosis, cc, is 1/1700 or 0.00059, then the frequency of the c allele is sqrt (0.00059) = 0.0243 or about 2.4%

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A question asked by jedi knight: Does anyone have cystic fibrosis please help me?
ok so ive been going to the doctor for about 2 year and they just told me they thing they know whats wrong with me they think i have cystic fibrosis because they did the sweat test and it was high but there gonna redo the test and do more test to make sure i have it.. do you i have it? they said if i have its a mild case. how long do people with mild case have to live ? tell me about your life if you have cf and how it is with doctor and treatment and stuff tell me about it thank i would appreciated it

Selected answer:

Answer by Kelly H
If the sweat test came back positive then it is likely that you do have CF. Another sweat test and a DNA test will verify the diagnosis.

My seven year old daughter has Cystic Fibrosis. There are over 1,000 different Cystic Fibrosis mutations and even people with the same genetic defect have different symptoms. My daughter’s genetic defect affects both her lungs and her digestion and we knew as soon as she was born that something was wrong. If you are old enough to post this question and you are only now getting sweat tested then I am guessing that your symptoms are on the milder side and that is why your doctor is telling you that if you have Cystic Fibrosis that it is a milder case. There are people in their sixties that have Cystic Fibrosis. I believe these are the people who fall into the milder case category.

Three pieces of advice if you indeed have CF:
1. Limit your research about CF on the Internet. www.cff.org is the CF website and it is very informative. I say this because the personal situations that are posted are often not the norm and it is highly unlikely that they will apply to your case. And as I said, each person with CFs situation is different. Feel free to contact me at any time if I can be of any help.
2. Find a good CF clinic and a CF doctor that you like and feel comfortable talking to. We went through several doctors before we found the right one for us.
3. Make your health a priority. If you are prescribed breathing treatments, medications, etc. Make sure that you do them. They are not an option. Use a lot of hand sanitizer and have the people around you use it too.

My daughter’s life is not a good representation of someone with a milder case but it will give you an idea of what it is like to live with CF. Important…my daughter’s CF situation would not be considered mild so her treatments and therapies may not apply to someone with a milder case of CF. She has to take enzymes with anything that she eats to help her digest her food. She has to eat double the calories of someone her age to maintain or gain weight. She does breathing treatments twice a day and uses a vibrating vest to help loosen mucus in her lungs. She does the breathing treatments and the vest more often when she is sick. She also has some other medications that she takes. She goes to the CF clinic every eight weeks to have her lungs and weight checked. Overall I would say that her life is not easy. But CF is a part of who she is. She is a lot of fun, she loves life and she finds joy in everything. All of the people that I have met with CF are like that.
There are two drugs that are in phased trial testing that show extreme promise for helping to correct the CF defect within a person’s cells. So, there is realistic hope that a cure will be found.

Do you know better? Why not leave your own answer in the comments below!

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Probability Help Please!!!!!!!!!!!!!!!?

A question from Ty: Probability help please!!!!!!!!!!!!!!!?
Genetic testing reveals that two newlyweds are both carriers of the recessive mutation that causes cystic fibrosis. As a consequence, any child produced by the marriage has a probablility of 1/4 of being afflicted with cystic fibrosis. If this couple has three children (none being identical siblings), what is the probablility that….
(a) none of the children will have cystic fibrosis?
(b) at least one child will have cystic fibrosis?
(c) one child will have cystic fibrosis and the other two will not?
(d) the last born child will have cystic fibrosis, given that you already know that the first two have cystic fibrosis?

The best answer:

Answer by Gerry
a) Since there is a (1/4) chance of a child getting cystic fibrosis, there is a (1 – (1/4)) = (3/4) chance of a child not getting it. If three in a row are not to get it the probability is:

(3/4)^3 = (27/64) < -------------------- Answer to (a)
------------------

b) This is the opposite of none getting it (see (a) above) and that is (1 - (27/64)) = (37/64)
------------------

c) (1/4) * (3/4) * (3/4) * 3 = (27/64)
------------------

d) The first two do not affect the third, they are independent of each other and are called independent events.

(1/4) <----------------- Answer to (d)

.

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Question by Amy P: Another Hardy-Weinberg Problem. Please HELP!!?
After graduation, you and 19 friends build a raft, sailed to a deserted island, and start a new population, totally isolated from the world. Two of your friends carry (heterozygous for) the receive allele , which in homozygotes causes cystic fibrosis.

a. assuming that the frequency of this allele does not chance as the population grows, what will be the instance of cystic fibrosis on the island?

b. calculate how many times grater cystic fibrosis births on the island are vs. the original mainland. The frequency on mainland is .059%.

Best answer:

Answer by Asst Prof
You and your 19 friends have 40 alleles. Since 2 are carriers, there are 2 n alleles and 38 N alleles (where N=a normal allele). So the frequency of n = 2/40 = 0.05 and the frequency of N = 1-0.05 = 0.95. In the future population, the frequency of cystic fibrosis, nn, will be 0.05↑2 = 0.0025 or 0.25%.

If CF on the mainland is 0.059% or 0.00059, then 0.0025/0.00059 = about 4.24 times more CF on the island.

If you know better then please let us know below.

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Question by Sadsadsad Sadsadsadas: Can anyone please answer these questions on cystic fibrosis?
cystic fibrosis
1. What is the cause of this disease? Gene therapy is a possibility for future treatments.
2.What are the pros and cons of gene therapy.
3. What are the pros and cons of genetic testing for this disease (cystic fibrosis) ?
4.Who should be tested?
5. Who should be able to access the results of the genetic test results of a genetic test (parents, doctors, patients, insurance companies, etc.)

Best answer:

Answer by gangadharan nair
Cystic Fibrosis: This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

Whether you agree or disagree, why not leave your own thoughts below.

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Cystic Fibrosis GENETICS PLease Help!!!?

Question posed by katya K: Cystic fibrosis GENETICS PLease help!!!?
I need to know 10 genetic concepts that are related to cystic fibrosis…such as complementation, inheritance, allelism, etc. I dont know if those apply or not. If you cant give me 10 its ok just as many as you can.

Chosen answer:

Answer by legalbgl
I know its inherited. Check out their website for all the details.

How about adding your own answer to the comments below!

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