Cystic Fibrosis

by windy_sydney

A question asked by Nikki:Cystic fibrosis (CF) is caused by a recessive allele. A child has Cystic Fibrosis, even though neither of his parents……
…….has CF. If this couple has another child, what is the probability he or she will NOT have Cystic Fibrosis?

a. 3/4
b. 2/3
c. 2/4
d. 1/3
e. 1/4

Top answer:

Answer by Dsf S
3/4

How about adding your own answer to the comments below!

Technorati Tags: allele, caused, child, cystic, even, fibrosis, neither, Parents, Recessive, though

by windy_sydney

A question from Lorry Gregory: AP Biology homework help about Cystic Fibrosis?
Cystic fibrosis can be caused by any one of several mutant alleles of the cystic fibrosis gene. The most common of these mutants alleles accounts for about 70% of cases of cystic fibrosis. The use of gene probes can identify individuals carrying this allele. Gene probes are single strands of DNA which are radioactively labelled. They have a base sequence that is complementary to a mutant allele. The main stages in using a gene probe are shown in the diagram.
Sample of DNA extracted from a person’s tissue and heated to separate the strands.
Radioactive gene probe is added to the DNA.
Excess probe is washed away.
Sample is tested for radioactivity.
Using the information given, explain how the use of a gene probe could enable the presence of a mutant allele of the cystic fibrosis to be detected.

Chosen answer:

Answer by Horst S
With your approach, you can only identify those mutations that you actually test for.
You take a sample of your extracted DNA and separate it into various aliquots. Each aliquot is individually hybridized with a probe specific for each mutation. This can be done by Southern Hybridization. You will get a signal when your sequence binds (hybridizes) with the probe. No signal means that mutation is absent – the probe could not bind.

If you know better then please let us know below.

Technorati Tags: about, Biology, cystic, fibrosis, help, homework

by Office of Governor Patrick

Question posed by 22akgirl: Questions on cystic fibrosis!!?
what organism(s) does cystic fibrosis affect and how?
how frequently does the mutation occur
what are some high-risk demographics?
what is the average life expectancy?
what is the death rate
what are some treatments?

thanks:)
i meant demographics not demographies:)

No 1 answer:

Answer by Matt A
http://www.mamashealth.com/cfibrosis.asp

http://www.wrongdiagnosis.com/c/cf/stats.htm

http://www.disabled-world.com/health/respiratory/cystic-fibrosis/life-expectancy.php

http://www.cff.org/AboutCF/

Try these websites to answer your question.

If you know better then please let us know below.

Technorati Tags: cystic, fibrosis, questions

A question asked by cnaines: What is the ethnic group affected by Cystic Fibrosis?
an inherited/ genetic disease that …..source http://www.cff.org/AboutCF/Faqs/#Who_gets_cystic_fibrosis?

Cystic fibrosis is an inherited disease that causes thick, sticky mucus to build up in the lungs and digestive tract. It is the most common type of chronic lung disease in children and young adults, and may result in early death

Chosen answer:

Answer by Mariah
White, European descendents mostly get the disease, although there are always a small percent of other ethniticities that get it.

Agree or disagree? Leave your own thoughts below.

Technorati Tags: affected, cystic, ethnic, fibrosis, group

A question asked by milelj79: Cystic Fibrosis in newborns? Do you have a child with CF?
Cystic fibrosis in newborns? Do you have a child with CF?
My daughter will be two weeks old tomorrow. We got a call from the pediatrician today that her newborn screening tests came back and she needs to go having further screening to test for cystic fibrosis. Did anyone have to do this and have the tests come back negative that they don’t have it? Neither me or my husband have a family history of CF, so this was a surprise. I’m very worried and hoping it’s a false alarm.

Does anyone have a child with CF? What symptoms did they have as a newborn?

I did read about CF online, but am curious about what other people have experienced with their babies.

Thanks for any information you have.

The No 1 answer:

Answer by E M
Here’s a link I found about the testing.

http://www.cysticfibrosismedicine.com/htmldocs/CFText/screen.htm

And here’s a very good article all about it

http://children.webmd.com/tc/Cystic-Fibrosis-Topic-Overview

I hope your daughter is ok!

In order for your child to have CF, both parents have to be a carrier of CF. If only one parent is a carrier, the child will not have CF. They must inherit it from both parents.

Agree or disagree? Leave your own thoughts below.

Technorati Tags: child, cystic, fibrosis, newborns

Question by AJ S: Questions about Cystic Fibrosis?
I was just wondering if a toddler could be diagnosed with cystic fibrosis even if they haven’t exhibited respiratory symptoms. anyone have any information for a scared mommy waiting for a phone call?

The No 1 answer:

Answer by Hattie
Yes, sorry to say it bluntly though! Try not to worry, I’m sure they will be fine, and even if the news is that they have CF, there are plenty of helping hands out there. Your not on your own, so don’t worry!

Hope your both okay!

Provide your own answer to this question below!

Technorati Tags: about, cystic, fibrosis, questions

A question asked by toni.chang: In Finland, the frequency of heterozygous carriers of cystic fibrosis is 1/80.?
In Finland, the frequency of heterozygous carriers of cystic fibrosis is 1/80. In a small Finnish city there is a Swedish immigrant community in which the heterozygous carrier frequency for cystic fibrosis is 1/22. What is the probability that a child born to a Finnish mother and a father from this Swedish population will suffer from the disease?

Chosen answer:

Answer by Peter S
1/80 x 1/22 = 1 in 1760

If you know better then please let us know below.

Technorati Tags: 1/80., carriers, cystic, fibrosis, Finland, frequency, heterozygous

A question asked by Becky; ♥: if the male has cystic fibrosis, and the female is a carrier, what is the percentage their child will have it?
is it 50%?

No 1 answer:

Answer by Joshua D
yep cos its a recessive allele

Whether you agree or disagree, why not leave your own thoughts below.

Technorati Tags: Carrier, child, cystic, female, fibrosis, male, percentage, their

A question from laziedazie: In Cystic Fibrosis a change in a single gene causes the protein called CFTR to??
a. become less soluble
b. fold improperly
c. transport sodium ions instead of chloride ions

Chosen answer:

Answer by ewtaylor2001
b.

What do you think? Leave you answer below!

Technorati Tags: called, causes, CFTR, change, cystic, fibrosis, gene, protein, single

by Office of Governor Patrick

Question by Mei: Cystic Fibrosis question: in 1950s (and before) life expentcancy was only about 1 year,?
whereas today it is currently 38.4, and rapidly extending. So life expectency is 38 times more in about 50 years.

In which years was the biggest jump in life expentancy and what medical development was primarly the cause of this jump?

What i mean is, was there some treatment that was invented that all of sudden made L.E. for CF 10 times what it was, and when did this happen?

The No 1 answer:

Answer by pollypocket8282
I think medically Pulmozyme was the start of the L.E. jumps. cff has a timeline if you want to see what was established when…
I know when pulmozyme first came out I went from doing IV antibiotics 2-3 times a year to going 2 years Healthy without ANY Antibiotics.

http://www.cff.org/research/ResearchMilestones/

Whether you agree or disagree, why not leave your own thoughts below.

Technorati Tags: 1950s, about, before, cystic, expentcancy, fibrosis, life, only, question, year