A question from : Is albuteral nebulizer treatment save for a 10 month old baby?
Just diagnosed with cystic fibrosis. His lung x-rays are clear. His digestive system is the problem area. Why would they automatically put him on these treatments?

The best answer:

Answer by Toccare questo e muoiono jeralyn is here!!!!
http://en.wikipedia.org/wiki/Cystic_fibrosis probably because of frequent lung infections resulting in difficulty breathing lungs get mucus build up decreased air exchange

If you know better then please let us know below.

Technorati Tags: albuteral, baby, month, nebulizer, save, treatment

Question by summer: What are the rules of inheritance for Cystic Fibrosis?
Can the children be carriers of Cystic Fibrosis if the father has Cystic Fibrosis, but the mother does not?

My chosen answer:

Answer by CC
If the father has CF then the child is guaranteed to be a carrier whether the mother is a carrier or not.

Whether you agree or disagree, why not leave your own thoughts below.

Technorati Tags: cystic, fibrosis, inheritance, rules

by cstmweb

A question from Tigerlily2682: Part 1: Genetics – From Genes to Proteins, Mutations (Chapter 10)?
Overview: Genetic information in DNA is transcribed to RNA and then translated into the amino acid sequence of a Protein.

A) Step 1 – Transcription: During the process of transcription, the information in the DNA codons of a gene is transcribed into RNA.

Suppose that gene X has the DNA base sequence 3’-TACCCTTTAGTAGCCACT-5’.

Question: What would be the base sequence of RNA after transcription occurs? Turn this in.

(In this particular example, assume that the RNA product does not require processing to become mRNA. In other words, the transcribed RNA becomes the mRNA sequence.)

B) Step 2 – Translation: During protein synthesis at the ribosome, the base sequence of the mRNA codons is translated to the amino acid sequence of a protein.

Question: Using the mRNA that you transcribed above, use the genetic code table to determine the resulting amino acid sequence? Turn this in.

And, turn in the answer to these questions:

What is the significance of the first and last codons? What meaning do these codons have for protein synthesis?

C) Mutations: A mutation is defined as a change in the base sequence of DNA. This may occur as a “mistake” in DNA replication, for example.

Suppose that during DNA replication, two mutant DNA sequences are produced as shown below.

For the 2 mutated DNA sequences, you will investigate how these changes might affect the sequence of amino acids in a protein.

Question: For each of the two, you will need to first transcribe the mRNA, and then use the genetic code table to determine the amino acid sequence.

Turn these in, and state whether the protein sequence changes for each.

Question: Then, explain why a change in amino acid sequence might affect protein function. Turn in your answer.

Here is the original sequence, followed by two mutated sequences, 1 and 2:

Original sequence 3′- TACCCTTTAGTAGCCACT-5’

Mutated sequence 1) 3’-TACGCTTTAGTAGCCATT-5′

Mutated sequence 2) 3’-TAACCTTTACTAGGCACT-5’.

Part 2: Inheritance of Traits or Genetic Disorders (Chapter 12)

Bob and Sally recently married. Upon deciding to plan a family, both Sally and Bob find out that they are both heterozygous for cystic fibrosis, but neither of them has symptoms of the disorder.

Set up and complete a Punnett Square for cystic fibrosis for this couple; turn in the Punnett square.

When doing the Punnett Square, C = normal allele; and c = allele for cystic fibrosis.

Note: You can use the Table function in MS Word to create and fill in a Punnett Square.

Questions:

Based on the Punnett square, calculate chances (percentages) for having a healthy child (not a carrier), a child that is a carrier for the cystic fibrosis trait, and a child with cystic fibrosis? Turn in these percentages.

Part 3: Cell division, sexual reproduction and genetic variability (Chapter 11)

Eukaryotic cells can divide by mitosis or meiosis. In humans, mitosis produces new cells for growth and repair; meiosis produces sex cells (gametes) called sperm and eggs.

Although mutations are the ultimate source of genetic variability, both meiosis and sexual reproduction also can contribute to new genetic combinations in offspring.

Question: How do both meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents? Be sure to talk about steps in meiosis that increase variability as well as the process of fertilization.

Most detailed answer:

Answer by Kendi Rosenberg
part one:
A) AUGGGAAAUCAUCGGUGA
B) AUG(the start code/ methoninie), GGA (Glycine), AAU (Asparagine), CAU (Histidine), CGG (Arginine), UGA (Stop code)

The significance of the fist and last codons are that theay are the start code and the stop code.

The meaning they have for protien synthesis is that the start code tells where to start synthesis and the stop code tells where to stop synthesis.

C) Mutated sequence 1) AUGCGAAAUCAUCGGUAA
AUG (start code/ methonine), CGA (Arginine), AAU (Asparagine), CAU (Histidine), CGG (Arginine), UAA (Stop code)

Mutated sequence 2) AUU GGA AAU GAU CCG UGA
AUU (Lisoleucine), GGA (Glycine), AAU (Asparagine), GAU (Aspartic acid), CCG (Proline), UGA (Stop code)

The Change in Amino Acid sequence might effect the protien function because for example in mutated sequence number 2 there is no start code meaning this would never get translated.

Part 2:

Here i drew a punnet square for you and took a picture of it… here is the link

They have a 25% chance of having a child that is not a carrier.
They have a 50% chance having a child who is a carrier.
They have a 25% chance of having a child has cystic fibrosis
1:2:1 – genotypic
3:1- phenotypic

Part 3:

Meiosis and sexual reproduction contribute to genetic variation by independant assortment- random distribution of homologus churomosomes. Also by crossing over and random fertalization.

How about adding your own answer to the comments below!

Technorati Tags: Chapter, from, Genes, GENETICS, Mutations, part, Proteins

Question posed by MKM: A medical question on Cystic Fibrosis?
My niece who is 25 and recently found out she is 7 weeks pregnant has just been diagnosed as a carrier of cystic fibrosis, she has never had any symptoms of the disease my ?’s are,
How will this affect her child or could it, and how can a person be a carrier without any symptoms? Also there is now history at least on the mothers side.

No 1 answer:

Answer by Doxycycline
Cystic fibrosis is what is called an “autosomal recessive” disease. This means that for your niece’s daughter to have CF, Dad would also have to be a carrier for CF OR have CF himself.
If Dad is neither a carrier nor a victim of CF, there is a possibility for the child to be a carrier of CF but this will not harm the child and it will not be an issue until it comes time for the child to have kids of his/her own.

Provide your own answer to this question below!

Technorati Tags: cystic, fibrosis, medical, question

A question asked by TeddyGrahams: GENETICS GENETICS GENETICS…?
Polydactyly is a dominant trait caused by the gene P, as opposed to the unaffected allele p. Cystic Fibrosis, c, is a recessive disease, as opposed to the unaffected condition, C. A Polydactylous woman, otherwise unaffected in phenotype, marries a healthy unaffected man. THeir four children have the following phenotypes: child 1 is unaffected, Child 2 is polydactylous, otherwise unaffected, child 3 has cystic fibrosis, otherwise unaffected, Child 4 has cystic fibrosis and is polydactylous.
A. What is the genotype of the mother?
B. What is the genotype of child 3?
C. What is the genotype of Child 4?
D. What is the chance that child 1 is heterozygous for cysitic fibrosis?

The No 1 answer:

Answer by Kelly
A. The mother is Pp Cc – this is b/c to have any children that are unaffected for Polydactyly she must carry the recessive unaffected gene but since she is affected she must also have the dominant gene – and she is unaffected for cystic fibrosis so she must have the dominant C and to have kids w/ cystic fibrosis she must also carry the recessive gene b/c for the kids to be affected they must be cc.

B. Dad must be pp Cc – so child 3 must be pp cc

C. Pp cc

D. Since the dominant C is unaffected and mom is Cc and dad is Cc then an unaffected child could be CC or Cc – so 50% chance of being heterozygous (different alleles)

What do you think? Leave you answer below!

Technorati Tags: GENETICS

A question asked by Jilly: Can cystic fibrosis cause a miscarriage?
I am a carrier for Cystic Fibrosis. I’m not sure if my boyfriend is (he’s getting a blood test done) but I just had a miscarriage and my doctor said that MAY be the reason why. I’ve had a miscarriage before too, I’m just wondering if this could have caused it? =[

Top answer:

Answer by veronica P
my close friend in middle school got pregnant our 8th grade year and she has cystic fibrosis, the doctor said it could of been becasue of age or the disease

Whether you agree or disagree, why not leave your own thoughts below.

Technorati Tags: cause, cystic, fibrosis, Miscarriage

A question asked by cindy 529: What are the genotypic and phenotypic ratios of offspring when male and female carriers of cystic fibrosis m?
If you know the answer please help me and if you also know what is the genotype of a person that is the carrier of a disease and also what is the genotype of a person that has a disease it is because i get confused if it is Aa or aa for a person that has a disease or just carries it.

The No 1 answer:

Answer by Strut Your Stuff
Cystic fibrosis (CF) = autosomal recessive disease. You therefore need two copies of the gene to have the phenotype (i.e. show the disease). SO let’s say:

A = dominant (normal) allele
a = recessive (CF) allele

1. A normal non-carrier will have the genotype AA
2. A carrier (asymptomatic) will have the genotype Aa / aA [sometimes they write it both ways; it means the same thing]
3. A CF sufferer (symptomatic) will have the genotype aa

Agree or disagree? Leave your own thoughts below.

Technorati Tags: carriers, cystic, female, fibrosis, genotypic, male, Offspring, phenotypic, ratios

A question asked by High or Something: Cystic fibrosis?
I dont have Cystic fibrosis but I am a carrier of it. What are the chances that my children will be carriers.
and are there any side effects of being a carrier?

My chosen answer:

Answer by ohno
if your husband is also a carrier of that gene, your children will have a high chance..
im not sure of the percentages, but if you are the only one that carries that gene, it is more unlikely

Agree or disagree? Leave your own thoughts below.

Technorati Tags: cystic, fibrosis

by k-ideas

Question posed by BobbyBill: Please Help: Genetics questions?
1. Is it possible for incomplete dominant and codominant alleles to be homozygous and heterozygous?

2. Would a karyoptype reveal the presence of cystic fibrosis, sickle-cell disease and hemophilia?

3. Also, can somebody explain to me about multiple allele traits and multiple gene traits? How are they the same, and how are they different?

My chosen answer:

Answer by Asst Prof
1. Yes, since heterozygous means “having different seeds,” a genotype showing two different alleles, LIke RW (for pink flowers) or AB (for blood type AB) is technically heterozygous. Similarly, if both alleles are the same, the gene is homozygous (having the same seed),

2. No. Those are defects in alleles, which cannot be seen on a karyotype. A karyotype will show only *chromosome* defects (like extra or broken chromosomes).

3. Most genes have ony 2 alleles, like red or white flowers, or tall or short. Genes with more than 2 alleles are cases of multiple allelic genes; human blood types are an example, with 3 alleles, A, B, and i. Multiple gene traits are traits that are controlled by more than one gene, all exerting their effects. Human skin tone is thought to be the result of 12 genes exerting their effects; thsi is why we have a wide range of skin colors, not just black or whte.

If you know better then please let us know below.

Technorati Tags: GENETICS, help, PLease, questions

A question asked by decemberkitty02: If two parents are carriers of cystic fibrosis (and do not have the disorder), what is the probability?
If two parents are carriers of cystic fibrosis (and do not have the disorder), what is the probability that their first child will have CF and their second child will not?

I thought that it would 3/16s? Is this correct?

The No 1 answer:

Answer by Russ
Theyre both Aa, so its {AA,Aa,Aa,aa}, so P(having the disease) = 1/4, and P(not having the disease) = 3/4
Multiply the two and you get 3/16. So you are correct

Agree or disagree? Leave your own thoughts below.

Technorati Tags: carriers, cystic, disorder, fibrosis, Parents, Probability