love:) asked:

my husband and i want to have a baby but we both carry the cystic fibrosis gene and are afraid of the baby having cf. we already have a boy with it and he’s doing great but im afraid if we have another one it will be bad. advice anyone

doubleOshoe asked:

Which of the following genotypes represent people who have the cystic fibrosis phenotype:

CC
or
Cc
or
cc

Southern Bell asked:

My twin daughters are four and they want a dog or a cat but they have Cystic Fibrosis so I’m worried about the animal hair and germs from the animals if I got them pets because they are very prone to infections already and I’ve never had any animals around them in our house before. Would having dogs and/or cats around them be a problem?

Greta asked:

I found out that my twin daughters have cystic fibrosis, what is the average current life-expectancy for people with this disease and how can the you maximize their life expectancy?

Cystic fibrosis (CF) is the most common hereditary chronic disease of the mucus and sweat glands. It largely affects the lungs, pancreas, sex organs, intestines, liver, and sinuses. The condition is due to a defective gene that produces an irregularly shaped form of a cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is a type of protein that is essential to the body.

People having cystic fibrosis do not have enough CFTR for their cells to work normally because their bodies quickly destroy the mutant CFTR. Majority of Cystic Fibrosis cases result from the lack of an essential amino acid building block in the CFTR, causing it to fold into its characteristic and functional three-dimensional structure abnormally. A protein that fails to fold into the intended shape usually produces inactive proteins with different characteristics. This is how CF affects the mucus and sweat glands.

Normally, mucus is watery, thus keeping the linings of certain organs are moist and keeps them from drying out or getting infected. But in the case of CF, the abnormally shaped CFTR causes mucus to become thick and sticky. The mucus tends to build up in your lungs and block the airways. The condition is then a potent venue for bacteria to grow causing serious lung infections, which will eventually damage the lungs. The most common cause of death of CF patients is respiratory failure.

In the same way, mucus build up can block ducts in the pancreas. With this, digestive enzymes produced by the pancreas, will not be able to reach the small intestine. These pancreatic enzymes are responsible for breaking down dietary nutrients in order for the body to efficiently absorb fats and proteins. Moreover, the abnormally shaped protein or CFTR can induce your body to withdraw large amounts of salt, upsetting the mineral balance in your body.

A specific treatment plan is required for each particular CF condition. For cystic fibrosis affecting the lungs, regular chest physiotherapy, an average of two time daily, is very important. This procedure helps clear away the thick mucus in the airways.

Exercise is also beneficial. It helps regulate blood and oxygen circulation as well as encourage muscle function in the body. Inhalers and oxygen are also helpful in this lung disease for it can open up the airways.

Antibiotics and antifungals are standard part of the treatment and are usually taken for long periods. It helps with the inflammation and pain. The dosage and type of the medications would depend on the type of bacteria infecting the body and the severity of the disease. Also, others may decide to take proteolytic enzyme supplements such as serrapeptase or treatments to help in clearing inflammation and mucus.

For people with CF that primarily affecting the digestie system, they must take enzyme supplement. People with such disease will have difficulty in absorbing certain nutrients due to the decreased digestive enzymes. Thus, taking enzyme supplements such as lipase alongside a diet high in fat and carbohydrates is a standard treatment.

By: Paul S Fitzgerald

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Shay H asked:

They want to test my husband for the gene as well, they said I don’t have cystic fibrosis but i carry the gene, does that mean my baby will have it?

mizzck asked:

I know there are many other info vidz on Cystic fibrosis but i thought it was about time 4 a updated vid.This is an information video to bring cystic fibrosis:a genetically inherited & life-threatening condition, into the spotlight.CF is a common condition which need the help and support of everyone to fight against CF. At this moment in time,there is no cure for cystic fibrosis but we hope 2 find it one day with your help.Plz pass this video on to everyone you know;the more ppl that are aware of CF,the quicker we can get to finding that cure,plz help us see off CF.thank you. [sufferer of CF]

lildevil_883 asked:

Hi I’m 26 male and I have cf and I live in central Illinois and was looking for other people that have and would like to talk and share advice

razzldazzl1212 asked:

i’ve researched cystic fibrosis and tay-sachs disease for a biology project. we’re supposed to include a picture of a karyotype, but neither of them have karyotypes that portray the disorder. someone said it’s because the mutation is too small for a karyotype, but is that true for almost all autosomal genetic diseases, other than down’s syndrome?

+ are there karyotypes for hemophilia, william’s syndrome, or leukodystrophy?

thanks!

nalla asked:

has anyone with cystic fibrosis ever been on Acutane, (an acne med). If so, could you tell me of any problems you experienced while on Acutane?