A question from laziedazie: In Cystic Fibrosis a change in a single gene causes the protein called CFTR to??
a. become less soluble
b. fold improperly
c. transport sodium ions instead of chloride ions

Chosen answer:

Answer by ewtaylor2001
b.

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Technorati Tags: called, causes, CFTR, change, cystic, fibrosis, gene, protein, single

GENETICS QUESTION!!!?

Question posed by Sarah Boo: GENETICS QUESTION!!!?
A mother with cystic fibrosis marries a man who is a carrier of cystic fibrosis. What are the chances their child will be a carrier of the disease?

Most detailed answer:

Answer by DAVID HENDER
50% chance the child will be a carrier and 50% chance they will have cystic fibrosis as it is a recessive disorder.
So 50%

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Technorati Tags: GENETICS, question

Question by Mei: Cystic Fibrosis question: in 1950s (and before) life expentcancy was only about 1 year,?
whereas today it is currently 38.4, and rapidly extending. So life expectency is 38 times more in about 50 years.

In which years was the biggest jump in life expentancy and what medical development was primarly the cause of this jump?

What i mean is, was there some treatment that was invented that all of sudden made L.E. for CF 10 times what it was, and when did this happen?

The No 1 answer:

Answer by pollypocket8282
I think medically Pulmozyme was the start of the L.E. jumps. cff has a timeline if you want to see what was established when…
I know when pulmozyme first came out I went from doing IV antibiotics 2-3 times a year to going 2 years Healthy without ANY Antibiotics.

http://www.cff.org/research/ResearchMilestones/

Whether you agree or disagree, why not leave your own thoughts below.

Technorati Tags: 1950s, about, before, cystic, expentcancy, fibrosis, life, only, question, year

A question from Lulu: Can cystic fibrosis damage the brain during embryotic development?
I know that Cystic Fibrosis is a chronic disease of the lungs and digestive system that causes the body to produce mucus. . . But, can cystic fibrosis damage the brain during embryotic development? I thought it could because the mucus build-up could block oxygen from reaching the brain, causing damage and poor development. . .
Please include a source. . .

Most detailed answer:

Answer by hels
no not at all

If you know better then please let us know below.

Technorati Tags: brain, cystic, damage, development, during, embryotic, fibrosis

Genetics Problems W/ PUNNET SQUARES?

A question from s3jealousy: Genetics Problems w/ PUNNET SQUARES?
Please I am so lost with this.

1. In humans, blue eyes are recessive to brown eyes. Draw a punnet square showing the expected ratios of chilren born to a blue-eyed woman and a brown-eyed man whose mother was blue eyed.

2. In cats, short hair is dominant to long hair. A shorthaired tomcat is mated to a longhaired female. She has eight kittens: 6 shorthaired and 2 longhaired. Diagram the cross. How do the results compare to the expected ratios?

3. Cystic fibrosis is recessively inherited trait. Two normal people have a child who has cystic fibrosis. What was the probability that this couple produces a child with cystic fibrosis. What is the probablility that this couple will have two children in a row afflicted with cystic fibrosis?

4. The gene for red/green eye color vision is sex-linked. Red/green color blindness is recessive. Would the children of a color-blind woman and a man of normal color vision be color-blind?

5. The chestnut color of horses is due to a recessive gene, while the dominant allele results in a black coat. In terms of gaits, a horse may be a trotter (dominant) or a pacer (recessive). By means of a Punnet Square, show the offspring which could result from a cross between a black trotter whose mother was a chestnut pacer and a black pacer whose father was chestnut.

6. Listed below are the progeny from two crosses between a species of flowering plants. What pattern of inheritance does this cross illustrate? Determine the genotypes of the parents and their progeny. Draw a punnet square to validate your answers. Show all work.
– Cross 1: blue-flowered plant X white-flowered plant gives F1: all pale-blue flowered
– Cross 2: pale-blue F1 X pale-blue F1 gives F2: 27 blue, 49 pale-blue, and 24-white flowered plants.

Most detailed answer:

Answer by Dina Felice
1. bb (woman) x Bb (man)

___ B | b
b | Bb | bb

2. Ss x ss

___ S | s
s | Ss | ss

We would expect 50-50, so 75-25 is unexpected. It is as if the female was also heterozygous, instead of homozygous long.

3. 25% or 1/4.
6.25% or 1/16

4. The sons would all be colorblind, none of the daughters would be, but all the daughters would be carriers.

5. BbTt x Bbtt

You would see 4 possible phenotypes, black trotters, black pacers, chestnut trotters and chestnut pacers, but it is 32 squares, so I’m not going to write it out.

6. This is incomplete dominant. You are crossing 2 true breeding flowers, then getting all heterozygous offspring, then normal 1:2:1 ratio in F2.

Provide your own answer to this question below!

Technorati Tags: GENETICS, problems, PUNNET, SQUARES

Question posed by allyson2626: Cystic Fibrosis Testing and the R117H Gene?
My doctor just called and I have test positive as a cystic fibrosis carrier. We are still waiting on the results of my husband’s test. On top of this I have a mutation in my gene called a R117H. He said it may cause sterilization if this is a boy. I am having trouble finding any information written in lay men’s terms. Does anyone know any additional information? Has anyone had this? What is the likelihood that this will cause sterilization if it is a boy?

Thanks so much. I am trying not to worry, but I would like to be informed before they send me to a specialist…

Selected answer:

Answer by Bellangel
Check out the website below that is where this statement comes from.

Cystic fibrosis is a genetic disease that is associated with abnormal sweat electrolytes, sino-pulmonary disease, exocrine pancreatic insufficiency, and male infertility.

Here is another site you might find out some more information.

Hope these two site will be help to you. Good luck

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Technorati Tags: cystic, fibrosis, gene, R117H, Testing

Chances of My Baby Having Cystic Fibrosis?

A question asked by L: Chances of my baby having cystic fibrosis?
My twin sister has cystic fibrosis, I’m a carrier of it but I don’t have it myself. My boyfriend is getting tested next week to see if he is a carrier of it too (he’s of european decent). What are the chances that my baby would have it?

Best answer:

Answer by flash
im 13 but i know alot ur a carrier ur baby will have it most lickly carrier gives it to their baby ALL the time so yea shes going to have it if im wrong thank god

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Technorati Tags: baby, chances, cystic, fibrosis, having

Cystic Fibrosis?

A question from NICU_nurse_2012: Cystic Fibrosis?
I have just gotten tested for carrying the Cystic Fibrosis gene yesterday. Has anyone been tested for this and came up positive? My fiance is a carrier of the gene, and before ttc, we just wanted to make sure that everything is ok with me. Even if I am positive as a carrier, can we still have a baby that does not have cystic fibrosis?

Chosen answer:

Answer by Joe B
Yes

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Technorati Tags: cystic, fibrosis

Genetics Problem ?????????????

A question from Helen: Genetics Problem ?????????????
Cystic fibrosis is a serious genetic disease caused by an autosomal recessive allele (C= normal and c= cystic fibrosis). This trait is not rare amongst humans; approximately 1 in 25 people in human populations are carriers (i.e. heterozygous for this allele). A woman and her husband (neither of whom have the disease) are considering having children, but the woman’s brother (there were only two children in the family) has cystic fibrosis. On the other hand, the woman’s parents and her maternal grandparents (i.e. her mother’s parents) did not have the disease.

a. Draw a partial pedigree showing all of the individuals mentioned and give their genotypes as fully as possible (hint: there may be uncertainty for some).

b. What is the33 probability that the first child produced by this couple will have cystic fibrosis?

No 1 answer:

Answer by Elisa
use a punnett square. its not that difficult.

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Technorati Tags: GENETICS, problem

Genetics Question for Biology?

Question by edgygirl: Genetics question for Biology?
imagine that you are a genetic counselor, and a couple planning to start a family comes to you for information. Charles was married once before, and he and his first wife had a child with cystic fibrosis. The brother of his current wife, Elaine, died of cystic fibrosis. What is the probability that Charles and Elaine will have a child with cystic fibrosis. Neither Charles or Elaine has cystic fibrosis.
I know the answer is 1/6 but how do you get that?
how many punnet squares do i draw? and put what on each of the two sides. thats what i need help with.

No 1 answer:

Answer by Yote
do a punnet square!

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Technorati Tags: Biology, GENETICS, question

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