How Do Chloride Ions Affect Water Transport and Mucus Buildup in Cystic Fibrosis?

A question from kyhoops819: How do chloride ions affect water transport and mucus buildup in cystic fibrosis?
In the disease cystic fibrosis there is a defect in the ability of endothelial cells to transport Cl- ions. What rationale would this have on water balance and possible regulation of mucus build up in the lungs? Since this defect is in a gene for all cells would other tissues besides the lungs be influence, if so, which ones and why? Besides gene therapy, what pharmacological treatments are beneficial and why for treating the Cl- ion imbalance?

Top answer:

Answer by W
Osmosis baby.

For the rest, read your damn notes or textbook. This is not a cheating service.

Do you know better? Why not leave your own answer in the comments below!

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Filed under: Cystic Fibrosis

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